Combination Therapy with Methotrexate and Etanercept for Refractory Chronic Recurrent Multifocal Osteomyelitis: Figure 1.
نویسندگان
چکیده
منابع مشابه
Combination therapy with methotrexate and etanercept for refractory chronic recurrent multifocal osteomyelitis.
Chronic recurrent multifocal osteomyelitis (CRMO) is a form of chronic nonbacterial osteitis (CNO) characterized by one or more lytic bone lesions with no identifiable cause1. The metaphyses of long bones and the clavicle are most frequently affected, although any bone may be involved. Most cases begin in childhood, and follow an intermittent course. Pain is the most common presenting symptom. ...
متن کاملImaging of refractory chronic recurrent multifocal osteomyelitis succesfully treated with etanercept and methotrexate
Methods A 5-year-old boy presented with a 1 year history of right leg pain with limited range of motion and difficulty in walking due to flexion, abduction and external rotation of right hip attitude. No fever. Plain radiographs were normal. In the blood test, elevation of acute phase reactants was detected: ESR 41 mm/h, CRP 2.27 mg/dL. A Whole Body MRI (WB-MRI) scan revealed osteitic multifoca...
متن کاملChronic recurrent multifocal osteomyelitis; manifestation, imaging and diagnosis
Chronic recurrent multifocal osteomyelitis (CRMO) is an inflammatory bone disease usually affecting children. A 9-year old boy presented with recurrent lower extremities pain and discomfort lasting for two years. In every time, symptoms vanished after several weeks. The patient received antibiotics only in one period of bone pain. In other occasions the patient didn’t received any antibiotics. ...
متن کاملChronic recurrent multifocal osteomyelitis.
Chronic recurrent multifocal osteomyelitis is an autoinflammatory disorder characterized by bone pain and fever, a course of exacerbations and remissions, and a frequent association with other inflammatory conditions. Because its etiology is largely unknown, the diagnosis is still based on clinical criteria; treatment is empiric and not always successful. The diagnosis is supported by the prese...
متن کاملChronic Recurrent Multifocal Osteomyelitis in a 9-year-old Boy
Chronic recurrent multifocal osteomyelitis (CRMO) is a rare aseptic, auto-inflammatory bone disorder. CRMO presents with bone pain with or without fever. The diagnosis of CRMO is a diagnosis of exclusion and should be included in the differential diagnosis of chronic inflammatory bone lesions in children. Cultures of the bone are typically sterile, antibiotic therapy does not result in clinic...
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ژورنال
عنوان ژورنال: The Journal of Rheumatology
سال: 2011
ISSN: 0315-162X,1499-2752
DOI: 10.3899/jrheum.100431